Company OverviewAt GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, focusing our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. GSK has kicked off 2025 with growth in sales, profits, and earnings, with expectations for new FDA product approvals and pivotal study readouts. By uniting science, technology, and talent, we are committed to getting ahead of disease together.Job PurposeWe are seeking an experienced, motivated and innovative individual to join us as a Director in the Translational & Clinical Genetics team, part of the GSK Human Genetics and Genomics organisation. The successful candidate will provide strategic leadership and undertake hands-on analyses to identify, develop and deliver a portfolio of translational data-driven activities to impact the GSK portfolio. You will have strong expertise in genetics, with emphasis on causal inference approaches, and demonstrable experience integrating genetics with genomics (especially proteomics) and clinical phenotypic data. Your work will inform target discovery, biomarker discovery, disease and mechanistic understanding, indication and patient subgroup selection, and parsing treatment response using precision medicine approaches.The successful candidate will lead a team of direct reports in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and leaders from various functions and external collaborators to advance drug discovery and clinical development. You will have the opportunity to identify, establish and oversee collaborations with external institutions aligned with strategic priorities, and will be supported in developing scientific leadership through impactful work, presenting research and publishing peer-reviewed papers.Key responsibilitiesThis role will provideYOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:Utilize deep expertise in statistical genetics and the integration of genetics with genomic (including proteomics) and clinical phenotypic data to generate at-scale insights and address translational scientific questions.Provide strategic leadership and hands-on analytical work to identify, develop, and deliver programs of work to impact the GSK drug development pipeline.Work within and lead cross-functional GSK project teams, with emphasis on respiratory, hepatology, neurodegeneration, immunology and/or renal disease.Identify, set up and oversee external scientific collaborations.Effectively communicate analysis findings to project teams within and outside the GSK Human Genetics & Genomics organisation.Work with focus and agility to deliver personal and team deliverables against objectives, demonstrating strong statistical, analytic and critical thinking skills with understanding of the translational context of the work.Stay informed about emerging technologies and methodologies in translational genetics and causal inference approaches, evaluating their potential and implementation in the organization as indicated.Lead a team of direct reports and foster a culture of innovation, collaboration, and continuous professional learning.Basic QualificationsPhD or equivalent advanced degree in a relevant scientific discipline (e.g. statistical genetics, genetic epidemiology, biomedical statistics, computational sciences, bioinformatics or machine learning) with impactful scientific publications and/or presentations.Extensive experience in genetics and analyses that integrate genetics, genomics (particularly proteomics) and/or clinical phenotypic data to address translational questions in drug discovery and development.Expertise in genetic causal inference approaches (Mendelian randomization) with understanding of emerging methodologies.Ability to develop and implement new methodologies to integrate genetics and genomics to answer translational questions in drug discovery and development.Demonstrated ability to address key scientific questions with innovative analytical solutions impacting the drug discovery pipeline.Strong proficiency in at least one of R and Python, with a track record of writing reproducible, scalable code that adheres to FAIR principles.Experience in line management and supporting professional development of team members.Demonstrated ability to communicate complex scientific concepts to diverse audiences.Preferred QualificationsExcellent collaboration and partnership skills to work effectively with internal stakeholders across functions.Experience setting up and overseeing external collaborations.Experience working in different trusted research environments (TREs).Ability to work independently and in multidisciplinary teams to meet project timelines.Familiarity with stages of drug discovery and development.Why GSK? Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, focusing on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases.We are committed to creating an environment where our people can thrive and focus on what matters most. Our culture is ambitious for patients, accountable for impact and doing the right thing, guiding how we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures all qualified applicants receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under applicable law.We believe in an agile working culture for all roles. If flexibility matters to you, explore what opportunities exist with our hiring team. For adjustments to our process, contact UKRecruitment.Adjustments@gsk.com or 0808 234 4391. The helpline is available 8:30am–12:00 noon, Monday to Friday. For other inquiries, please refer to the UK Recruitment FAQ guide.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or agencies for vacancies posted on this site. Prior written authorization is required before referring candidates to GSK. This is a condition precedent to any agreement between the agency and GSK. GSK shall not be liable for fees arising from such referrals. For US licensees, GSK may capture and report expenses to ensure compliance with federal and state transparency requirements. More information is available at openpaymentsdata.cms.gov. #J-18808-Ljbffr