We are seeking an experienced, motivated and innovative individual to join us as an Associate Director, Statistical Pharmacogenetics in the Translational & Clinical Genetics team.The successful candidate will design and deliver hands-on pharmacogenetic statistical analyses of clinical trial data, working in cross-functional teams to impact the GSK portfolio. You will have strong expertise in genetics and experience of undertaking genetic analysis of clinical trial data.The successful candidate will work directly with colleagues in Human Genetics and Genomics and closely with a range of other stakeholders in matrix teams, including but not limited to clinical statisticians and biomarker project leads.In this role you will:Conduct hands-on pharmacogenetic analyses of clinical trials.Design and author statistical analysis plans and pharmacogenetic reports.Collaborate and work closely with colleagues in cross-functional teams to oversee the development and timely delivery of pharmacogenetic analyses and reports.Perform a range of statistical genetic analyses including, but not limited to, power calculations, single variant tests, burden tests, and polygenic risk scores.Integrate genetics and other omics data in analyses to gain novel translational insights.Understand the strengths and limitations of different statistical genetic analyses for pharmacogenetics.Evaluate and implement new methodologies and technologies to improve the efficiency and effectiveness of genetic analyses.Ensure compliance with relevant regulations and guidelines in the field of pharmacogenetics.Qualifications & Skills:We are looking for a professional with these required skills to achieve our goals:PhD or equivalent advanced degree in a relevant scientific discipline (e.g. statistical genetics, genetic epidemiology, biomedical statistics, computational sciences, bioinformatics) with a history of impactful scientific publications and/or presentations.Expertise in statistical geneticsExperience of conducting genetic analyses of clinical trial dataStrong written communication skills to design and write pharmacogenetic statistical analysis plans and reports.Strong proficiency in at least one of R and Python, with experience of writing reproducible and scalable code that abides to FAIR principles.Excellent collaboration and partnership skills to work effectively with internal stakeholders across functions.Demonstrated experience of effectively communicating complex scientific concepts to diverse audiences.Demonstrated ability to work effectively both independently and in multidisciplinary teams to meet project timelines.Preferred Qualifications & Skills:If you have the following characteristics, it would be a plus:Extensive experience in genetics and preferably conducting analyses that integrate genetics with other omics data to generate novel translational insights.Familiarity with the common statistical approaches used to analyse clinical trialsExperience of project management is desirable to enable oversight of pharmacogenetic studies from registration to archivingFamiliarity with the stages of drug discovery and developmentGSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. #J-18808-Ljbffr