Position: Medical Director

Location: Cambridge, United Kingdom

George Higginson is currently searching for an experienced Medical Director to play a pivotal role being 'hands-on' and to provide medical and scientific leadership for a Clinical-stage Biotech's Phase 2 and 3 clinical trials. This role will act as the internal medical expert and a key driver of trial strategy, oversight, and execution in a highly collaborative, cross-functional environment.

Main Responsibilities:

• Provide strategic and operational medical input into Phase 2/3 trials, including study design, execution, and analysis.
• Oversee CRO medical teams and ensure high-quality, GCP-compliant trial conduct.
• Perform medical data review and ensure adequate safety oversight in collaboration with Drug Safety.
• Develop and review key documents including protocols, IBs, safety updates, and CSRs.
• Contribute to regulatory interactions and submissions.
• Support DMCs and assure compliance with ICH-GCP and regulatory expectations.
• Collaborate with Clinical Operations and external partners throughout the trial lifecycle.
• Create and deliver medical training materials and support investigator meetings.

Requirements:

• Medical degree with at least 5 years of clinical research experience in biotech or pharma.
• Strong understanding of GCP and global clinical development processes.
• Proven ability to interpret complex clinical data and guide study-level decisions.
• Experience working within cross-functional teams and with external vendors (e.g. CROs).

'Nice-to-haves':

• Board certification or experience in Dermatology or Rheumatology.
• Previous involvement in regulatory interactions (e.g. EMA, FDA).
• Experience with Biologics or immunology programs.

What We’re Looking For:

• A hands-on medical leader who thrives in a dynamic, collaborative biotech environment.
• A strong communicator with sharp clinical and scientific judgment.
• Someone who can move seamlessly between strategic input and detailed oversight.

This is a fantastic opportunity to be a key part of a true-underdog clinical-stage Biotech, soon approaching a BLA submission.

Apply today to take the next step in your leadership journey!